Primary dysmenorrhea is the most common gynecologic problem in reproductive-age women. However, it is so familiar that many women fail to report it in medical interviews. As a result, said prevalence rates are as high as 80-90 percent even though statistical findings show 60-65% in most instances, and about 60% of the dysmenorrhea group is medium to severe.

Gynecologists seldom prescribe drugs for menstrual cramps because known analgesics cause damage to the reproductive system. What worries most is that pharmacologists have yet to deliver a safe and reliable medication for Menstruation-related Symptom (MRS). As a result, severe sufferers advise bearing cramps at home for one or two days. Most desperately call for the ultimate solution to release them from self-imprisonment every menstrual period.

These MRS have lower scores on quality of life such as general health and physical, mental, social, and occupational functioning during their periods. In addition, these symptoms may create considerable financial burdens on patients, their families, and society. Such outgoes relate to the costs of visits to the doctor, over-the-counter drugs, and medical or other Complementary and Alternative Medicine (CAM) treatments.

Menstrual pain is a common cause of school and works absenteeism. Productivity losses due to women’s desertion in the workplace are phenomenal, costing the US economy more than $2.0 and $8.5 billion in 1999 and 2019, respectively.